Disclaimer: This article is for educational purposes only and does not replace expert medical or mental health advice. Benadryl misuse and addiction require a comprehensive psychiatric and physical evaluation by a qualified clinician. So, always refer to a licensed mental health specialist for specialized medical advice.
Benadryl is often prescribed for allergies among children and adults. However, have you ever wondered if this commonly prescribed medication can become addictive? While not common, Benadryl can become addictive with frequent and prolonged use, like other household items, such as glue and whippets, misused for recreational reasons.
What Is Benadryl Prescribed For?
Benadryl is one of the popular brand names for the medication diphenhydramine, which is prescribed to treat:
- Fever
- Congestion
- Cough
- Irritated, itchy, and watery eyes
- Allergies.
Get Started With Nuview Treatment Center
Our dedicated professional staff is here to guide you or your loved one on the journey to lasting recovery, offering support every step of the way.
Can Benadryl Be Misused?
Benadryl is prescribed for specific purposes - but when it is used frequently and for a prolonged period of time, or in other ways than prescribed, it can be misused.
Benadryl is misused because it has sedative properties and can be used as a sleep aid. However, the U.S. Food and Drug Administration (FDA) has not approved diphenhydramine for sleep purposes. In fact, it also leads to other unwanted effects such as:
- Poor focus
- Reduced memory
- Poor education/job performance
- Increased risk of accidents and injuries.
What Are the Signs of Benadryl Misuse?
While Benadryl or diphenhydramine misuse is not categorized as a separate disorder in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR), some common signs of substance use disorder or addiction are:
- Using Benadryl more frequently, heavily, or in other ways than prescribed.
- Strong, persistent cravings to use Benadryl.
- Tried to quit Benadryl before, but have not been able to do so.
- Prioritizing Benadryl use over other things in life - such as education, job, or family.
- Continuing to use Benadryl despite its ill effects on physical and mental health.
- Using Benadryl in high-risk circumstances, like driving or operating heavy machinery.
- Developing tolerance for Benadryl, which means you need larger quantities of Benadryl to achieve the desired effects.
- Experiencing withdrawal symptoms like restlessness, sleep disturbances, and other discomforting symptoms upon abruptly reducing or stopping Benadryl use.
If you or someone you know is struggling with these symptoms, it may be an indication that you can benefit from substance use disorder treatment.
Get Started With Nuview Treatment Center
How Is Benadryl Addiction Treated?
Benadryl addiction can be treated with medically supervised detoxification and behavioral therapies. Currently, there are no FDA-approved medications to treat Benadryl misuse.
- Medical Detox: In detox, you stop using Benadryl so that it leaves your system. When it is performed under medically supervised conditions, it is safe, as a board-certified physician and psychiatric practitioner will be present with you.
- Psychotherapy: Behavioral therapies like motivational interviewing, cognitive behavioral therapy, contingency management, and 12-Step facilitation therapies uncover the underlying patterns leading to benadryl misuse and equip you with healthier coping mechanisms to handle life’s stressors and triggers.
If You Are Struggling With Benadryl Use, Reach Out Today
If you or someone you know is struggling with Benadryl misuse, reach out to the NuView Treatment Center today. We provide a full continuum of personalized outpatient care that is built around your life so that you can navigate daily responsibilities and recovery without having to choose between the two - at your own pace.
Please call us at (323) 307-7997 to explore your recovery options today!
Frequently Asked Questions About Benadryl Use and Misuse
What are the side effects of Benadryl?
While Benadryl is effective in treating allergies, it can lead to dry mouth and nose, drowsiness, dizziness, weakness, vision problems, and difficulty urinating.
How do I know I am misusing Benadryl?
If you are using Benadryl in other ways than prescribed, have strong cravings for Benadryl, and are hiding your Benadryl use from your loved ones, then these are some signs you may be misusing Benadryl.
Is Benadryl addictive?
Diphenhydramine is not classified as a highly addictive medication. However, repeated misuse, especially in high doses or for non-medical purposes, can lead to dependence and health risks. In fact, the National Center for Drug Abuse Statistics (NCDAS) says that an estimated 4.8% Americans misuse prescription medication in a year.
Can you overdose on Benadryl?
A person can overdose on Benadryl, and a severe overdose can be life-threatening, leading to seizures, coma, and even death. The U.S. Food and Drug Administration (FDA) even warns against the dangers of consuming high doses of diphenhydramine.
If you suspect a Benadryl overdose, it is a medical emergency. Call emergency providers like 9-1-1 (U.S.) or your local emergency providers (if you are outside the U.S.)
How can Benadryl addiction be treated?
Benadryl addiction can be treated with medical detox and behavioral therapies.
- What Is Benadryl Prescribed For?
- Can Benadryl Be Misused?
- What Are the Signs of Benadryl Misuse?
- How Is Benadryl Addiction Treated?
- If You Are Struggling With Benadryl Use, Reach Out Today
- Frequently Asked Questions About Benadryl Use and Misuse
- What Is Benadryl Prescribed For?
- Can Benadryl Be Misused?
- What Are the Signs of Benadryl Misuse?
- How Is Benadryl Addiction Treated?
- If You Are Struggling With Benadryl Use, Reach Out Today
- Frequently Asked Questions About Benadryl Use and Misuse
Get Help Today!
Everyone is Welcome Here and We All Have Your Back
Your healing journey deserves a personalized approach. At NuView, we integrate expertise in behavioral therapy, mental health, and substance use treatment to create a customized recovery plan tailored to your unique needs.
Connect with our Admissions Specialists today.







Written By
Dr. Ryan Peterson, MD